Fig. 3From: A computational study of the inhibition mechanisms of P-glycoprotein mediated paclitaxel efflux by kinase inhibitorsPaclitaxel and TKIs interact with the P-gp substrate-binding site. Predicted binding modes from docking studies of nilotinib (a), imatinib (b), dasatinib (c), and paclitaxel (d) in the substrate-binding pocket of P-gp, located on the left side of each panel and represented as color spheresBack to article page