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Table 4 Estimated parameters with CV 0.3 or less

From: Constraint-based perturbation analysis with cluster Newton method: a case study of personalized parameter estimations with irinotecan whole-body physiologically based pharmacokinetic model

ID: Parameters Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Patient 7
71: CLr (CPT-11) 0.10 0.07 0.12 0.11 0.18 0.25 0.18
72: CLr (SN-38) 0.28
76: CLbile (CPT-11) 0.10 0.10 0.18 0.10 0.13 0.30 0.20
80: CLbile (APC) 0.26 0.27
82: CLCES,2 0.27
83: CL3A4,1 0.12 0.08 0.12 0.08 0.23 0.28 0.18
  1. CV coefficient of variation, Bars represent CV is 0.3 over