Dengue virus causes changes of MicroRNA-genes regulatory network revealing potential targets for antiviral drugs

BMC Systems Biology

Table 2 Gene Ontology (GO) analysis of therapy target genes

Function Name	ID	Degree
Protein kinase	F008	118
regulation of cell proliferation	F003	102
regulation of programmed cell death and apoptosis	F001	100
response to cytokine stimulus	F004	86
protein amino acid phosphorylation	F007	86
immune response	F002	76
protein kinase cascade	F009	70
T cell receptor signaling pathway	F010	67
regulation of lymphocyte activation	F006	49
Toll-like receptor signaling pathway	F011	42
myeloid cell differentiation	F005	38
RIG-I-like receptor signaling pathway	F012	29

The degree shows scores of significantly enriched ‘Biological Process’ categories in GO relative to the target genes, (p value ≤ 0.05)

ISSN: 1752-0509