Fig. 4From: Linking physiologically-based pharmacokinetic and genome-scale metabolic networks to understand estradiol biologyPrediction of estradiol organ distribution. a estradiol organ concentrations were simulated over 15 hours following a 0.3mg i.v. bolus. b Predicted organ concentrations 1 hour following a 0.3mg i.v. bolus are compared to experimental data from the mouse, presented as mean (+/- s.d.) [48]Back to article page