Fig. 1
From: Modeling the therapeutic efficacy of NFκB synthetic decoy oligodeoxynucleotides (ODNs)
a Minimal model of NFκB signaling networks and the therapeutic strategy of NFκB synthetic decoy ODNs. Protein-binding Microarrays (PBMs) experiments indicate that the unbinding rates of genomic decoy sites (indicated in Fig. 1. as Decoy _1, 2…) follow a distribution plotted in Fig. 1a. b Oscillatory temporal dynamics of nuclear free NFκB and inhibitory effect of synthetic decoy ODNs