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Table 1 Prediction Evaluation (correlation coefficient)

From: In silico drug combination discovery for personalized cancer therapy

 

Model

Correlation coefficient

Correlation coefficient

Correlation coefficient

Correlation coefficient

   

(1700 samples with >10 or <-10)

(1177 samples with >15 or <-15)

(780 samples with >20 or <-20)

Linear

Elastic net

0.65

0.696

0.711

0.733

 

Ridge regression

0.661

0.717

0.742

0.752

Nonlinear

Kernel ridge regression (RBF)

0.728

0.773

0.795

0.822

 

Random forest

0.731

0.792

0.8

0.827

 

Extremely randomized trees

0.738

0.785

0.816

0.821

  1. Italicized values are the best performance for each experiment