From: In silico drug combination discovery for personalized cancer therapy
 | Model | Correlation coefficient | Correlation coefficient | Correlation coefficient | Correlation coefficient |
---|---|---|---|---|---|
 |  |  | (1700 samples with >10 or <-10) | (1177 samples with >15 or <-15) | (780 samples with >20 or <-20) |
Linear | Elastic net | 0.65 | 0.696 | 0.711 | 0.733 |
 | Ridge regression | 0.661 | 0.717 | 0.742 | 0.752 |
Nonlinear | Kernel ridge regression (RBF) | 0.728 | 0.773 | 0.795 | 0.822 |
 | Random forest | 0.731 | 0.792 | 0.8 | 0.827 |
 | Extremely randomized trees | 0.738 | 0.785 | 0.816 | 0.821 |