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Table 5 Topological parameters assessed in this study

From: Putative human sperm Interactome: a networks study

Parameter Definition
Connected Components It is the number of networks in which any two vertices are connected to each other by links, and which is connected to no additional vertices in the network.
Number of nodes It is the total number of molecules involved.
Number of edges It is the total number of interactions found.
Clustering coefficient It is calculated as CI = 2nI/kI(kI–1), where nI is the number of links connecting the kI neighbors of node I to each other. It is a measure of how the nodes tend to form clusters.
Network diameter It is the longest of all the calculated shortest paths in a network.
Shortest paths The length of the shortest path between two nodes n and m is L(n,m). The shortest path length distribution gives the number of node pairs (n,m) with L(n,m) = k for k = 1,2,…
Characteristic path length It is the expected distance between two connected nodes.
Averaged number of neighbors It is the mean number of connections of each node.
Node degree It is the number of interaction of each node.
Node degree distribution It represents the probability that a selected nodes has k links.
γ Exponent of node degree equation.
R2 Coefficient of determination of node degree vs. number of nodes, on logarithmized data.