Fig. 2
From: Evaluating model reduction under parameter uncertainty
Yeast glycolysis network. Each node is a compound and each arrow a reaction. Important compounds \(\mathcal {M}_{\mathrm {I}}\) and candidate compounds for reduction are specified by pink and black rectangles, respectively. NAD indicated by a cyan rectangle is not explicitly included in the model as the total amount of NAD and NADH is conserved. External fluxes are indicated by blue arrows. ∗, ⋆ and † show an irreversible reaction from NADH to NAD, a reversible reaction between NADH and NAD and an irreversible reaction from NAD to NADH, respectively. As indicated in the network, different types of these reactions bind to some of the fluxes