Multiple transcription factors contribute to inter-chromosomal interaction in yeast

BMC Systems Biology

Table 1 Significant TFs obtained using the Chi-square method and the multivariate regression model

Chi-square method			Multivariate regression model
TF	p < 0.05	Adjusted p < 0.05	TF	# times selected
Sut1	39	33	Cin5^a	2466
Azf1	38	34	Rlr1^a	2032
Cin5^a	38	23	Dig1^a	1558
Opi1^a	38	23	Ydr026c^a	1286
Gcr1	38	22	Sok2	1235
Stp1	37	27	Spt2^a	1037
Met4	36	23	Sko1^a	783
Spt2^a	34	16	Rlm1	556
Swi5	34	12	Adr1^a	458
Sko1^a	32	24	Ste12^a,b	381
Ste12^a,b	31	0	Hsf1^a	376
Rlr1^a	30	20	Uga3	360
Hsf1^a	30	15	Opi1^a	234
Tye7	29	20	Reb1	224
Cbf1	28	18	Pdr3	211
Phd1	28	14	Stb4	177
Skn7	26	15	Gat1	137
Ydr026c^a	26	1
Dig1^a	25	10
Adr1^a	25	8

^a Overlapping between two methods
^b Ste12 was not among the significant TF list but was manually selected because it contained more than 30 raw p < 0.05 and have several marginal adjusted p ~ 0.05

ISSN: 1752-0509