From: Analysis of significant protein abundance from multiple reaction-monitoring data
Interaction scenario | True subject type | True run type | Sample size | Model | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LMM | LR-SAM | ||||||||||||
Best | (FF) | (FR) | (RF) | (RR) | L | W | W 1 | W S | S VC | ||||
IS1 | Fixed | Fixed | 20 | 0.049 | 0.05 | 0.03 | 0.002 | 0.001 | 0.344 | 0 | 0 | 0.001 | 0.135 |
50 | 0.048 | 0.048 | 0.029 | 0.002 | 0 | 0.692 | 0.385 | 0.008 | 0.002 | 0.506 | |||
100 | 0.053 | 0.053 | 0.041 | 0.007 | 0.001 | 0.953 | 0.926 | 0.007 | 0.007 | 0.911 | |||
Random | 20 | 0.051 | 0.052 | 0.066 | 0.004 | 0.002 | 0.339 | 0.001 | 0.002 | 0.002 | 0.14 | ||
50 | 0.047 | 0.047 | 0.042 | 0.002 | 0.001 | 0.691 | 0.397 | 0.007 | 0.002 | 0.538 | |||
100 | 0.045 | 0.045 | 0.043 | 0.003 | 0.003 | 0.953 | 0.93 | 0.008 | 0.003 | 0.914 | |||
Random | Fixed | 20 | 0.147 | 0.149 | 0.198 | 0.051 | 0.046 | 0.402 | 0.001 | 0.009 | 0.027 | 0.213 | |
50 | 0.177 | 0.177 | 0.234 | 0.048 | 0.042 | 0.745 | 0.415 | 0.025 | 0.04 | 0.593 | |||
100 | 0.157 | 0.157 | 0.201 | 0.054 | 0.049 | 0.95 | 0.923 | 0.037 | 0.051 | 0.917 | |||
Random | 20 | 0.158 | 0.159 | 0.19 | 0.052 | 0.06 | 0.415 | 0 | 0.003 | 0.026 | 0.216 | ||
50 | 0.148 | 0.15 | 0.168 | 0.04 | 0.046 | 0.726 | 0.455 | 0.027 | 0.034 | 0.602 | |||
100 | 0.164 | 0.165 | 0.171 | 0.04 | 0.043 | 0.975 | 0.948 | 0.026 | 0.037 | 0.932 | |||
IS2 | Fixed | Fixed | 20 | 0.054 | 0.055 | 0.04 | 0.005 | 0 | 0.611 | 0.001 | 0.001 | 0.001 | 0.353 |
50 | 0.051 | 0.051 | 0.034 | 0.009 | 0.002 | 0.945 | 0.787 | 0.018 | 0.004 | 0.896 | |||
100 | 0.045 | 0.045 | 0.036 | 0.007 | 0.001 | 1 | 1 | 0.016 | 0.006 | 1 | |||
Random | 20 | 0.044 | 0.046 | 0.058 | 0.004 | 0.006 | 0.606 | 0 | 0.002 | 0.001 | 0.354 | ||
50 | 0.045 | 0.046 | 0.046 | 0.001 | 0.001 | 0.953 | 0.8 | 0.014 | 0.001 | 0.907 | |||
100 | 0.056 | 0.056 | 0.062 | 0.01 | 0.009 | 0.999 | 0.998 | 0.012 | 0.009 | 0.998 | |||
Random | Fixed | 20 | 0.145 | 0.147 | 0.2 | 0.055 | 0.046 | 0.592 | 0 | 0.005 | 0.033 | 0.44 | |
50 | 0.143 | 0.145 | 0.2 | 0.034 | 0.028 | 0.957 | 0.801 | 0.029 | 0.026 | 0.91 | |||
100 | 0.166 | 0.166 | 0.223 | 0.049 | 0.04 | 1 | 1 | 0.043 | 0.045 | 1 | |||
Random | 20 | 0.162 | 0.164 | 0.188 | 0.048 | 0.057 | 0.639 | 0 | 0.001 | 0.021 | 0.443 | ||
50 | 0.144 | 0.145 | 0.177 | 0.04 | 0.044 | 0.949 | 0.801 | 0.02 | 0.031 | 0.901 | |||
100 | 0.17 | 0.17 | 0.206 | 0.053 | 0.06 | 0.999 | 0.999 | 0.032 | 0.048 | 0.999 |