Fig. 5
From: Mechanistic insight into activation of MAPK signaling by pro-angiogenic factors
Predicted time response of pERK following stimulation by FGF, VEGF, and their combination. a T1, time to reach the maximum pERK in response to growth factor stimulation. Asterisk indicates statistically significant difference compared to corresponding VEGF concentration (p < 0.05). b T2, time that pERK is maintained above half of its maximum value in response to treatments. Each dot represents one fit. The dots are spread horizontally to avoid overlap of similar responses from different fits. Asterisk indicates statistically significant difference compared to corresponding FGF concentration (p < 0.05). Yellow: FGF; Blue: VEGF; Red: combination. Bars are median ± 95% confidence interval