Skip to main content


Fig. 3 | BMC Systems Biology

Fig. 3

From: DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression

Fig. 3

Ensemble model estimation and characterization procedure. (a-c) An ensemble of models with prediction error within a threshold was found by perturbing model parameters (keff). d Archetypal analysis was used to characterize the ensemble where any data point is approximated as a convex combination of archetypes. e The predicted time-course proteome profile from the ensemble with best fit to measured metabolite concentrations was compared with measured time-course expression profiles

Back to article page