Skip to main content


Fig. 3 | BMC Systems Biology

Fig. 3

From: Constructing network topologies for multiple signal-encoding functions

Fig. 3

Bi-functional networks via module combinations. (a), (b) and (c) depict the results for one-node, two-node, and three-node merging, respectively. In each subfigure of (a), (b), (c), the upper left panel shows the form of node merging; two nodes in an ellipse represent the nodes that are merged, and the bottom left panel is the Q1,2 distribution of the combined bi-functional networks. Clustering analyses of the networks with relatively high Q1,2-values as marked by dashed red box in the histogram are depicted in the middle. The structure skeletons are illustrated on the right. d-f Examples of bi-functional combined networks that contain implicit interactions due to the competitive effect. Competitive edges are indicated in blue or purple. The dashed linkages represent the implicit interactions

Back to article page