Skip to main content

Advertisement

Table 1 Optimal values of the parameters corresponding to patient ID71 from Yamamoto et al. [18]

From: Model-based virtual patient analysis of human liver regeneration predicts critical perioperative factors controlling the dynamic mode of response to resection

Parameter Optimized value Parameter Optimized value
M 5.8206 kdeg 6.9843
kIL6 1.4528 κECM 32.9924
κIL6 0.6878 kGF 0.1014
VJAK 20,000 κGF 0.2016
\( {\mathrm{K}}_{\mathrm{M}}^{\mathrm{JAK}} \) 9999.9999 kup 0.0589
κJAK 0.1695 kQP 0.0072
[proSTAT3] 1.9108 kPR 0.0045
VST3 749.9994 kRQ 0.0520
\( {\mathrm{K}}_{\mathrm{M}}^{\mathrm{ST}3} \) 0.1715 kprol 0.0232
κST3 0.0828 kreq 0.0912
VSOCS3 24,000.0000 θreq 7.9493
\( {\mathrm{K}}_{\mathrm{M}}^{\mathrm{SOCS}3} \) 0.0006 βreq 2.9285
κSOCS3 0.3173 kap 0.0982
\( {\mathrm{K}}_{\mathrm{I}}^{\mathrm{SOCS}3} \) 0.0153 θap 0.0321
VIE 249.9992 βap 0.0045
\( {\mathrm{K}}_{\mathrm{M}}^{\mathrm{IE}} \) 17.9736 kG 0.0007
κIE 4.9595