Skip to main content


Fig. 3 | BMC Systems Biology

Fig. 3

From: Network-based characterization of drug-protein interaction signatures with a space-efficient approach

Fig. 3

Example of drug-protein interaction signature: association between drug-chemical substructure (SKELETON C1b(N1d)-C1b(O7a) in KCF-S format) and biological pathway (hsa04080 Neuroactive ligand-receptor interaction). a Horizontal axis shows drugs sharing chemical substructure, and vertical axis shows proteins sharing biological pathway. Color of each element corresponds to number of databases storing corresponding interaction. b Chemical structures of drugs sharing substructure are shown, and extracted substructure is highlighted in red (see Table 1 for further details)

Back to article page