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Fig. 5 | BMC Systems Biology

Fig. 5

From: Network-based characterization of drug-protein interaction signatures with a space-efficient approach

Fig. 5

The association between KCF-S “RING C1x-C1x-C1y(C1z)-C1y(C1x)-C1y(C1x)-C1z(C1a+C1y)” and KEGG pathway module “hsa_M00110 C19/C18-Steroid hormone biosynthesis”. a The heat map shows the numbers of databases that register confirmed drug-protein interactions from KEGG, DrugBank, Matador, Chembl, PSD pi databases. Horizontal and vertical axes show drugs and proteins, respectively. Gray, blue, green, yellow, orange and red indicate that 0, 1, 2, 3, 4 and 5 databases contain the corresponding interaction. b Chemical structures of some drugs, where red areas (if any) show the extracted substructure indicated by KCF-S. See also Table 3

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