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Fig. 3 | BMC Systems Biology

Fig. 3

From: Identification of Hürthle cell cancers: solving a clinical challenge with genomic sequencing and a trio of machine learning algorithms

Fig. 3

Loss of Heterozygosity in Hürthle positive samples. a Affymetrix CytoScan array data on Hürthle tissues vs. non-Hürthle normal tissues. Each column represents one chromosome and each row represents one sample. The value in each cell is the proportion of the chromosome displaying LOH for a given sample. The samples are sorted in descending order for genome-wide LOH. b Chromosome-level LOH data from RNA-Seq Hürthle positive and Hürthle negative samples. Above the horizontal dashed line are Hürthle positive samples, below the dashed line are Hürthle negative samples. c Chromosome-level LOH data from RNA-Seq Hürthle positive, Neoplasm positive or Neoplasm negative samples. Above the horizontal dashed line are Hürthle positive, Neoplasm positive samples, below the dashed line are Hürthle positive, but Neoplasm negative samples. For both (b) and (c) the LOH scale is to the right, with red indicating more LOH

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