Fig. 1
From: A mathematical model of iron import and trafficking in wild-type and Mrs3/4ΔΔ yeast cells
Strategy for optimizing a model of nutrient iron import, trafficking and regulation in growing eukaryotic cells. Top panel: C1 model in which all iron in the cell is treated as a single species and the cell is considered to be homogeneous. Middle panel: C3 model in which the cell is divided into three regions and each region is assumed to contain a single type of iron species. C4 model includes the reaction forming CIA. Bottom panel: C9 model in which the cell remains divided into 3 regions but the number of iron-containing species is expanded to 8