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Volume 10 Supplement 2

Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine 2015: systems biology


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editor declares that they have no competing interests.

Washington, DC, USA9-12 November 2015

Conference website

Other articles from the conference have been published as supplements to BMC Bioinformatics, BMC Genomics, BMC Medical Genomics and BMC Medical Informatics and Decision Making.

Edited by Xiaohua Hu.

  1. Networks provide effective models to study complex biological systems, such as gene and protein interaction networks. With the advent of new sequencing technologies, many life scientists are grasping for user-...

    Authors: Juli Petereit, Sebastian Smith, Frederick C. Harris Jr and Karen A. Schlauch
    Citation: BMC Systems Biology 2016 10(Suppl 2):51
  2. Wnt signal transduction pathway (Wnt STP) is a crucial intracellular pathway mainly due to its participation in important biological processes, functions, and diseases, i.e., embryonic development, stem-cell m...

    Authors: Losiana Nayak, Nitai P. Bhattacharyya and Rajat K. De
    Citation: BMC Systems Biology 2016 10(Suppl 2):44
  3. Various approaches to calling single-nucleotide variants (SNVs) or insertion-or-deletion (indel) mutations have been developed based on next-generation sequencing (NGS). However, most of them are dedicated to ...

    Authors: Yongchao Liu, Martin Loewer, Srinivas Aluru and Bertil Schmidt
    Citation: BMC Systems Biology 2016 10(Suppl 2):47
  4. Methods for inferring signaling networks using single gene knockdown RNAi experiments and reference networks have been proposed in recent years. These methods assume that RNAi information is available for all ...

    Authors: Yuanfang Ren, Qiyao Wang, Md Mahmudul Hasan, Ahmet Ay and Tamer Kahveci
    Citation: BMC Systems Biology 2016 10(Suppl 2):53
  5. Gene expression is mediated by specialized cis-regulatory modules (CRMs), the most prominent of which are called enhancers. Early experiments indicated that enhancers located far from the gene promoters are often...

    Authors: Seong Gon Kim, Nawanol Theera-Ampornpunt, Chih-Hao Fang, Mrudul Harwani, Ananth Grama and Somali Chaterji
    Citation: BMC Systems Biology 2016 10(Suppl 2):54