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Volume 10 Supplement 4

Proceedings of the 27th International Conference on Genome Informatics: Systems Biology


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Shanghai, China3-5 October 2016

Conference website

Edited by Shuigeng Zhou, Yi-Ping Phoebe Chen and Hiroshi Mamitsuka

Related articles have been published in supplements to BMC Bioinformatics and BMC Genomics.

  1. Protein-protein interface holds important information of protein-protein interactions which play key roles in most biological processes. In the past few years, a lot of efforts have been made to improve interf...

    Authors: Wentao Dai, Aiping Wu, Liangxiao Ma, Yi-Xue Li, Taijiao Jiang and Yuan-Yuan Li
    Citation: BMC Systems Biology 2016 10(Suppl 4):112
  2. It is necessary and essential to discovery protein function from the novel primary sequences. Wet lab experimental procedures are not only time-consuming, but also costly, so predicting protein structure and f...

    Authors: Quan Zou, Shixiang Wan, Ying Ju, Jijun Tang and Xiangxiang Zeng
    Citation: BMC Systems Biology 2016 10(Suppl 4):114
  3. Aging is a complex process relating multi-scale omics data. Finding key age markers in normal tissues could help to provide reliable aging predictions in human. However, predicting age based on multi-omics dat...

    Authors: Yin Wang, Tao Huang, Lu Xie and Lei Liu
    Citation: BMC Systems Biology 2016 10(Suppl 4):132
  4. Drought tolerance is an important trait related to growth and yield in crop. Until now, drought related research has focused on coding genes. However, non-coding RNAs also respond significantly to environmenta...

    Authors: Inuk Jung, Hongryul Ahn, Seon-Ju Shin, Jukon Kim, Hawk-Bin Kwon, Woosuk Jung and Sun Kim
    Citation: BMC Systems Biology 2016 10(Suppl 4):115
  5. Aberrant epigenetic modifications, including DNA methylation, are key regulators of gene activity in tumorigenesis. Breast cancer is a heterogeneous disease, and large-scale analyses indicate that tumor from n...

    Authors: Heejoon Chae, Sangseon Lee, Kenneth P. Nephew and Sun Kim
    Citation: BMC Systems Biology 2016 10(Suppl 4):116
  6. MicroRNAs (miRNAs) are involved in many biological processes by regulating post-transcriptional gene expression. The alterations of the regulatory pathways can cause different diseases including cancer. Althou...

    Authors: Shuqin Zhang and Michael K. Ng
    Citation: BMC Systems Biology 2016 10(Suppl 4):117
  7. High-throughput technology could generate thousands to millions biomarker measurements in one experiment. However, results from high throughput analysis are often barely reproducible due to small sample size. ...

    Authors: Cong Liu, Jianping Jiang, Jianlei Gu, Zhangsheng Yu, Tao Wang and Hui Lu
    Citation: BMC Systems Biology 2016 10(Suppl 4):118
  8. Measures of gene functional similarity are essential tools for gene clustering, gene function prediction, evaluation of protein-protein interaction, disease gene prioritization and other applications. In recen...

    Authors: Zhen Tian, Chunyu Wang, Maozu Guo, Xiaoyan Liu and Zhixia Teng
    Citation: BMC Systems Biology 2016 10(Suppl 4):119
  9. Protein-protein interactions (PPIs) are essential to most biological processes. Since bioscience has entered into the era of genome and proteome, there is a growing demand for the knowledge about PPI network. ...

    Authors: Yu-An Huang, Zhu-Hong You, Xing Chen and Gui-Ying Yan
    Citation: BMC Systems Biology 2016 10(Suppl 4):120
  10. Gene Ontology (GO) is a collaborative project that maintains and develops controlled vocabulary (or terms) to describe the molecular function, biological roles and cellular location of gene products in a hiera...

    Authors: Guoxian Yu, Wei Luo, Guangyuan Fu and Jun Wang
    Citation: BMC Systems Biology 2016 10(Suppl 4):121
  11. One of the most challenging tasks in the exploration of anti-aging is to discover drugs that can promote longevity and delay the incidence of age-associated diseases of human. Up to date, a number of drugs, in...

    Authors: Hui Liu, Mengmeng Guo, Ting Xue, Jihong Guan, Libo Luo and Ziheng Zhuang
    Citation: BMC Systems Biology 2016 10(Suppl 4):131
  12. Although there have been many studies revealing that dynamic robustness of a biological network is related to its modularity characteristics, no proper tool exists to investigate the relation between network d...

    Authors: Cong-Doan Truong, Tien-Dzung Tran and Yung-Keun Kwon
    Citation: BMC Systems Biology 2016 10(Suppl 4):122