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Volume 12 Supplement 1

Selected articles from the 16th Asia Pacific Bioinformatics Conference (APBC 2018): systems biology


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Yokohama, Japan15-17 January 2018

Conference website

Edited by Yi-Ping Phoebe Chen, Yasubumi Sakakibara and Yoshihiro Yamanishi

Related articles have been published as a supplement to BMC Bioinformatics and BMC Genomics.

  1. A network motif is a sub-network that occurs frequently in a given network. Detection of such motifs is important since they uncover functions and local properties of the given biological network. Finding moti...

    Authors: Kingshuk Mukherjee, Md Mahmudul Hasan, Christina Boucher and Tamer Kahveci
    Citation: BMC Systems Biology 2018 12(Suppl 1):6
  2. 25% of breast cancer patients suffer from aggressive HER2-positive tumours that are characterised by overexpression of the HER2 protein or by its increased tyrosine kinase activity. Herceptin is a major drug u...

    Authors: Petronela Buiga, Ari Elson, Lydia Tabernero and Jean-Marc Schwartz
    Citation: BMC Systems Biology 2018 12(Suppl 1):11
  3. Current technology has demonstrated that mutation and deregulation of non-coding RNAs (ncRNAs) are associated with diverse human diseases and important biological processes. Therefore, developing a novel compu...

    Authors: Takuya Mori, Hayliang Ngouv, Morihiro Hayashida, Tatsuya Akutsu and Jose C. Nacher
    Citation: BMC Systems Biology 2018 12(Suppl 1):37
  4. Microbial abundance profiles are applied widely to understand diseases from the aspect of microbial communities. By investigating the abundance associations of species or genes, we can construct molecular ecol...

    Authors: Mengxuan Lyu, Jiaxing Chen, Yiqi Jiang, Wei Dong, Zhou Fang and Shuaicheng Li
    Citation: BMC Systems Biology 2018 12(Suppl 1):5
  5. Drug-drug interactions (DDIs) always cause unexpected and even adverse drug reactions. It is important to identify DDIs before drugs are used in the market. However, preclinical identification of DDIs requires...

    Authors: Hui Yu, Kui-Tao Mao, Jian-Yu Shi, Hua Huang, Zhi Chen, Kai Dong and Siu-Ming Yiu
    Citation: BMC Systems Biology 2018 12(Suppl 1):14
  6. Signaling pathways can be reconstructed by identifying ‘effect types’ (i.e. activation/inhibition) of protein-protein interactions (PPIs). Effect types are composed of ‘directions’ (i.e. upstream/downstream) a...

    Authors: Soorin Yim, Hasun Yu, Dongjin Jang and Doheon Lee
    Citation: BMC Systems Biology 2018 12(Suppl 1):9