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Volume 12 Supplement 7

From Genomics to Systems Biology


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Edited by Hongwei Ge and Xiang Qin.

  1. Accumulation of amyloid β-peptide (Aβ) is implicated in the pathogenesis and development of Alzheimer’s disease (AD). Neuron-enriched miRNA was aberrantly regulated and may be associated with the pathogenesis ...

    Authors: Ling Hu, Rong Zhang, Qiong Yuan, Yinping Gao, Mary Q. Yang, Chunxiang Zhang, Jiankun Huang, Yufei Sun, William Yang, Jack Y. Yang, Zhen-li Min, Jing Cheng, Youping Deng and Xiamin Hu
    Citation: BMC Systems Biology 2018 12(Suppl 7):119
  2. Bladder cancer (BC) is the most common cancer of the urinary bladder and upper tract, in which the clinical management is limited. AURKA (aurora kinase A) has been identified as an oncogene in cancer developme...

    Authors: Mengjie Guo, Sicheng Lu, Hongming Huang, Yaohui Wang, Mary Q. Yang, Ye Yang, Zhimin Fan, Bin Jiang and Youping Deng
    Citation: BMC Systems Biology 2018 12(Suppl 7):118
  3. Reconstruction of gene regulatory networks (GRNs), also known as reverse engineering of GRNs, aims to infer the potential regulation relationships between genes. With the development of biotechnology, such as ...

    Authors: Bei Yang, Yaohui Xu, Andrew Maxwell, Wonryull Koh, Ping Gong and Chaoyang Zhang
    Citation: BMC Systems Biology 2018 12(Suppl 7):115
  4. Ecotoxicological studies on the insensitive munitions formulation IMX-101 and its components 2,4-dinitroanisole (DNAN), nitroguanidine (NQ) and nitrotriazolone (NTO) in various organisms showed that DNAN was t...

    Authors: Ping Gong, Keri B. Donohue, Anne M. Mayo, Yuping Wang, Huixiao Hong, Mitchell S. Wilbanks, Natalie D. Barker, Xin Guan and Kurt A. Gust
    Citation: BMC Systems Biology 2018 12(Suppl 7):92
  5. Adenocarcinoma in situ (AIS) is a pre-invasive lesion in the lung and a subtype of lung adenocarcinoma. The patients with AIS can be cured by resecting the lesion completely. In contrast, the patients with inv...

    Authors: Dan Li, William Yang, Carolyn Arthur, Jun S. Liu, Carolina Cruz-Niera and Mary Qu Yang
    Citation: BMC Systems Biology 2018 12(Suppl 7):117
  6. Single-cell RNA sequencing (scRNA-seq) technology provides an effective way to study cell heterogeneity. However, due to the low capture efficiency and stochastic gene expression, scRNA-seq data often contains...

    Authors: Mary Qu Yang, Sherman M. Weissman, William Yang, Jialing Zhang, Allon Canaann and Renchu Guan
    Citation: BMC Systems Biology 2018 12(Suppl 7):114

    The Correction to this article has been published in BMC Systems Biology 2019 13:13

  7. Autism Spectrum Disorder (ASD) is the umbrella term for a group of neurodevelopmental disorders convergent on behavioral phenotypes. While many genes have been implicated in the disorder, the predominant focus...

    Authors: Steven B. Cogill, Anand K. Srivastava, Mary Qu Yang and Liangjiang Wang
    Citation: BMC Systems Biology 2018 12(Suppl 7):91
  8. Nowadays, because of the huge economic burden on society causing by obesity and diabetes, they turn into the most serious public health challenges in the world. To reveal the close and complex relationships be...

    Authors: Guannan He, Yanchun Liang, Yan Chen, William Yang, Jun S. Liu, Mary Qu Yang and Renchu Guan
    Citation: BMC Systems Biology 2018 12(Suppl 7):116