Edited by Yuriy Orlov and Ancha Baranova.
Volume 13 Supplement 1
Selected articles from BGRS\SB-2018: systems biology
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. AB is co-author of one of the articles and review of the article was handled entirely by YO. No other competing interests were declared.
Novosibirsk, Russia20-25 August 2018
Citation: BMC Systems Biology 2019 13(Suppl 1):21
Towards embedding Caco-2 model of gut interface in a microfluidic device to enable multi-organ models for systems biology
A cancer cell line originating from human epithelial colorectal adenocarcinoma (Caco-2 cells) serves as a high capacity model for a preclinical screening of drugs. Recent need for incorporating barrier tissue ...Citation: BMC Systems Biology 2019 13(Suppl 1):19
Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster
The JAK/STAT signaling pathway is involved in many aging-related cellular functions. However, effects of overexpression of genes controlling JAK/STAT signal transduction on longevity of model organisms have no...Citation: BMC Systems Biology 2019 13(Suppl 1):16
Urine proteome changes associated with autonomic regulation of heart rate in cosmonauts
The strategy of adaptation of the human body in microgravity is largely associated with the plasticity of cardiovascular system regulatory mechanisms. During long-term space flights the changes in the stroke v...Citation: BMC Systems Biology 2019 13(Suppl 1):17
LSM-W2: laser scanning microscopy worker for wheat leaf surface morphology
Microscopic images are widely used in plant biology as an essential source of information on morphometric characteristics of the cells and the topological characteristics of cellular tissue pattern due to mode...Citation: BMC Systems Biology 2019 13(Suppl 1):22