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BMC Systems Biology

Volume 7 Supplement 4

Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine 2012: Systems Biology

Research

Edited by Xiaohua Hu

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editor declares that he no competing interests.

IEEE International Conference on Bioinformatics and Biomedicine 2012. Go to conference site.

Philadelphia, PA, USA4-7 October 2012

  1. Content type: Research

    Biomarker discovery holds the promise for advancing personalized medicine as the biomarkers can help match patients to optimal treatment to improve patient outcomes. However, serious concerns have been raised ...

    Authors: Jie Cheng, Joel Greshock, Leming Shi, Shu Zheng, Alan Menius and Kwan Lee

    Citation: BMC Systems Biology 2013 7(Suppl 4):S2

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  2. Content type: Research

    Study of biological networks is an essential first step to understand the complex functions they govern in different organisms. The topology of interactions that define how biological networks operate is often...

    Authors: Md Mahmudul Hasan, Yusuf Kavurucu and Tamer Kahveci

    Citation: BMC Systems Biology 2013 7(Suppl 4):S3

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  3. Content type: Research

    Multicolour Fluorescence In-Situ Hybridization (M-FISH) images are employed for detecting chromosomal abnormalities such as chromosomal translocations, deletions, duplication and inversions. This technique uses m...

    Authors: Jingyao Li, Dongdong Lin, Hongbao Cao and Yu-Ping Wang

    Citation: BMC Systems Biology 2013 7(Suppl 4):S5

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  4. Content type: Research

    The figures included in many of the biomedical publications play an important role in understanding the biological experiments and facts described within. Recent studies have shown that it is possible to integ...

    Authors: Luis D Lopez, Jingyi Yu, Cecilia Arighi, Catalina O Tudor, Manabu Torii, Hongzhan Huang, K Vijay-Shanker and Cathy Wu

    Citation: BMC Systems Biology 2013 7(Suppl 4):S8

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  5. Content type: Research

    The TNM staging system is based on three anatomic prognostic factors: Tumor, Lymph Node and Metastasis. However, cancer is no longer considered an anatomic disease. Therefore, the TNM should be expanded to acc...

    Authors: Ran Qi, Dengyuan Wu, Li Sheng, Donald Henson, Arnold Schwartz, Eric Xu, Kai Xing and Dechang Chen

    Citation: BMC Systems Biology 2013 7(Suppl 4):S9

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  6. Content type: Research

    Sets of genes that are known to be associated with each other can be used to interpret microarray data. This gene set approach to microarray data analysis can illustrate patterns of gene expression which may b...

    Authors: Rehman Qureshi and Ahmet Sacan

    Citation: BMC Systems Biology 2013 7(Suppl 4):S10

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  7. Content type: Research

    The analysis of RNA sequences, once a small niche field for a small collection of scientists whose primary emphasis was the structure and function of a few RNA molecules, has grown most significantly with the ...

    Authors: Lei Shang, David P Gardner, Weijia Xu, Jamie J Cannone, Daniel P Miranker, Stuart Ozer and Robin R Gutell

    Citation: BMC Systems Biology 2013 7(Suppl 4):S13

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  8. Content type: Research

    A fundamental issue in systems biology is how to design simplified mathematical models for describing the dynamics of complex biochemical reaction systems. Among them, a key question is how to use simplified r...

    Authors: Qianqian Wu, Kate Smith-Miles, Tianshou Zhou and Tianhai Tian

    Citation: BMC Systems Biology 2013 7(Suppl 4):S14

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