Investigating association between genes can be used in understanding the relations of genes in biological processes. STRING and GeneMANIA are two well-known web tools which can provide a list of associated gen...
Volume 9 Supplement 6
Joint 26th Genome Informatics Workshop and 14th International Conference on Bioinformatics: Systems Biology
Edited by Christian Shoenbach, Paul B Horton, Siu-Ming Yiu, Tin Wee Tan and Shoba Ranganathan
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for pubication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.
Joint 26th Genome Informatics Workshop and Asia Pacific Bioinformatics Network (APBioNet) 14th International Conference on Bioinformatics (GIW/InCoB2015). Go to conference site.
Tokyo, Japan9-11 September 2015
Citation: BMC Systems Biology 2015 9(Suppl 6):S1
Functional redundancy of transcription factors explains why most binding targets of a transcription factor are not affected when the transcription factor is knocked out
Biologists are puzzled by the extremely low percentage (3%) of the binding targets of a yeast transcription factor (TF) affected when the TF is knocked out, a phenomenon observed by comparing the TF binding da...Citation: BMC Systems Biology 2015 9(Suppl 6):S2
Biological processes at the molecular level are usually represented by molecular interaction networks. Function is organised and modularity identified based on network topology, however, this approach often fa...Citation: BMC Systems Biology 2015 9(Suppl 6):S3
Identification of network-based biomarkers of cardioembolic stroke using a systems biology approach with time series data
Molecular signaling of angiogenesis begins within hours after initiation of a stroke and the following regulation of endothelial integrity mediated by growth factor receptors and vascular growth factors. Recen...Citation: BMC Systems Biology 2015 9(Suppl 6):S4
Constructing a molecular interaction network for thyroid cancer via large-scale text mining of gene and pathway events
Biomedical studies need assistance from automated tools and easily accessible data to address the problem of the rapidly accumulating literature. Text-mining tools and curated databases have been developed to ...Citation: BMC Systems Biology 2015 9(Suppl 6):S5
In tumoral cells, gene regulation mechanisms are severely altered. Genes that do not react normally to their regulators' activity can provide explanations for the tumoral behavior, and be characteristic of can...Citation: BMC Systems Biology 2015 9(Suppl 6):S6