Volume 6 Supplement 3

The International Conference on Intelligent Biology and Medicine (ICIBM): Systems Biology

Research

Edited by Zhongming Zhao, Bing Zhang, Yufei Huang, Hua Xu and Yu Shyr

The conference was supported by a grant from National Science Foundation, USA (1141979) and financial support from the Center for Quantitative Sciences, Vanderbilt University. There was no sponsorship or other external funding for publication of the supplement.

The International Conference on Intelligent Biology and Medicine (ICIBM). Go to conference site.

Nashville, TN, USA

22-24 April 2012

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  1. Introduction

    Advances in systems biology: computational algorithms and applications

    The 2012 International Conference on Intelligent Biology and Medicine (ICIBM 2012) was held on April 22-24, 2012 in Nashville, Tennessee, USA. The conference featured six technical sessions, one tutorial sessi...

    Yufei Huang, Zhongming Zhao, Hua Xu, Yu Shyr and Bing Zhang

    BMC Systems Biology 2012 6(Suppl 3):S1

    Published on: 17 December 2012

  2. Research

    Module-based subnetwork alignments reveal novel transcriptional regulators in malaria parasite Plasmodium falciparum

    Malaria causes over one million deaths annually, posing an enormous health and economic burden in endemic regions. The completion of genome sequencing of the causative agents, a group of parasites in the genus Pl...

    Hong Cai, Changjin Hong, Jianying Gu, Timothy G Lilburn, Rui Kuang and Yufeng Wang

    BMC Systems Biology 2012 6(Suppl 3):S5

    Published on: 17 December 2012

  3. Research

    Mathematical modeling of left ventricular dimensional changes in mice during aging

    Cardiac aging is characterized by diastolic dysfunction of the left ventricle (LV), which is due in part to increased LV wall stiffness. In the diastolic phase, myocytes are relaxed and extracellular matrix (E...

    Tianyi Yang, Ying Ann Chiao, Yunji Wang, Andrew Voorhees, Hai-Chao Han, Merry L Lindsey and Yu-Fang Jin

    BMC Systems Biology 2012 6(Suppl 3):S10

    Published on: 17 December 2012

  4. Research

    Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data

    Interactions among genomic loci (also known as epistasis) have been suggested as one of the potential sources of missing heritability in single locus analysis of genome-wide association studies (GWAS). The com...

    Yu Liu, Sean Maxwell, Tao Feng, Xiaofeng Zhu, Robert C Elston, Mehmet Koyutürk and Mark R Chance

    BMC Systems Biology 2012 6(Suppl 3):S15

    Published on: 17 December 2012

  5. Research

    Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes

    Many genetic studies, including single gene studies and Genome-wide association studies (GWAS), aim to identify risk alleles for genetic diseases such as Type II Diabetes (T2D). However, in T2D studies, there ...

    Paul J Hale, Alfredo M López-Yunez and Jake Y Chen

    BMC Systems Biology 2012 6(Suppl 3):S16

    Published on: 17 December 2012

  6. Research

    Potential metabolic mechanism of girls' central precocious puberty: a network analysis on urine metabonomics data

    Central precocious puberty (CPP) is a common pediatric endocrine disease caused by early activation of hypothalamic-putuitary-gonadal (HPG) axis, yet the exact mechanism was poorly understood. Although there w...

    Linlin Yang, Kailin Tang, Ying Qi, Hao Ye, Wenlian Chen, Yongyu Zhang and Zhiwei Cao

    BMC Systems Biology 2012 6(Suppl 3):S19

    Published on: 17 December 2012

  7. Research

    Optimizing hybrid assembly of next-generation sequence data from Enterococcus faecium: a microbe with highly divergent genome

    Sequencing of bacterial genomes became an essential approach to study pathogen virulence and the phylogenetic relationship among close related strains. Bacterium Enterococcus faecium emerged as an important nosoc...

    Yajun Wang, Yao Yu, Bohu Pan, Pei Hao, Yixue Li, Zhifeng Shao, Xiaogang Xu and Xuan Li

    BMC Systems Biology 2012 6(Suppl 3):S21

    Published on: 17 December 2012

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