SHARKview: a tool for the visualization of systems biology data
© Pinney et al; licensee BioMed Central Ltd. 2007
Published: 8 May 2007
SHARKview is a freely available program to enable the interactive exploration of biological models encoded in the BioPAX or SBML exchange formats. This includes the ability to browse a model by pathway, physical entity, or interaction as well as the ability to overlay quantitative data such as gene expression levels onto the components of a model.
Using Saccharomyces cerevisiae models obtained from online resources in conjunction with expression data from several different studies, we show how SHARKview can be used to visualise mRNA expression level changes for the proteins composing a pathway. Pathways analysed include both metabolic and genetic regulatory pathways.
This article is published under license to BioMed Central Ltd.