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Table 3 Statistics of topology features and network motifs

From: Regulation patterns in signaling networks of cancer

  Comparative network motif Integration motif Maintenance motif Cluster coefficient Cluster coefficient
> 0
Information entropy
  normal tumor normal tumor normal tumor normal tumor normal tumor normal tumor
AML 1 3.94E+07 1.08E+07 541 27 6 26 0.126 0.113 1924 2344 10.94 12.35
AML 2 3.35E+07 3.35E+06 888 0 0 139 0.142 0.119 1373 1971 10.05 12.22
Breast 1 1.82E+07 1.88E+07 34 55 10 6 0.116 0.115 2234 2244 12.07 12.11
Breast 2 2.62E+07 2.39E+07 272 169 17 15 0.119 0.119 2271 2338 11.98 12.05
Cervical 1 5.04E+07 1.19E+07 614 49 4 52 0.134 0.117 1924 2538 10.89 12.12
Cervical 2 2.57E+07 1.74E+07 170 58 2 17 0.118 0.116 2081 2278 11.71 12.16
ESCC 2.52E+07 1.52E+07 70 8 0 6 0.117 0.112 2236 2435 11.99 12.55
Glioma 3.02E+07 2.28E+07 250 92 3 43 0.118 0.115 2242 2450 11.91 12.20
Head and neck 1.31E+07 1.24E+07 205 143 3 14 0.129 0.123 1712 1700 11.38 11.39
Lung 1 1.42E+07 1.40E+07 83 78 15 18 0.124 0.123 1813 1832 11.82 11.57
Lung 2 2.31E+07 1.88E+07 154 99 8 17 0.117 0.117 2137 2233 11.81 12.05
Oral tongue 1 1.84E+07 9.83E+06 231 68 1 32 0.130 0.121 1768 1912 11.42 12.04
Oral tongue 2 3.06E+07 2.15E+07 144 34 3 30 0.121 0.115 2349 2489 11.76 12.23
Pancreas 1 4.20E+07 1.37E+07 1427 115 5 79 0.123 0.114 1873 2457 11.23 12.21
Pancreas 2 4.60E+07 1.16E+07 1250 81 0 81 0.126 0.112 1866 2504 11.19 12.33
Prostate 1 1.37E+07 8.91E+06 573 398 0 3 0.130 0.126 1407 1485 11.06 11.30
Prostate 2 3.07E+07 2.29E+07 178 56 13 24 0.116 0.117 2357 2541 11.79 12.15
Renal 1 2.25E+07 2.24E+07 105 123 20 29 0.119 0.119 2181 2190 11.70 11.69
Renal 2 5.72E+07 7.05E+06 1227 116 8 116 0.138 0.118 1650 2398 10.56 12.16
Vulva 2.81E+07 2.67E+07 231 308 33 23 0.123 0.123 2299 2295 11.57 11.58
Tendency for tumor Down Down Up Down Up Up
Significance (P-value) 9.54E-06 5.53E-04 6.34E-04 1.05E-04 1.91E-05 8.20E-05