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Table 1 Information on the ethanol and lycopene models, their corresponding EMs, and their reaction and pathway change in Gibbs free energy.

From: Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design

  Ethanol Model Lycopene Model
Number of reactions 60 64
Number of metabolites 47 50
Mean EMA Computation Time (s) (± SD) 8.04 s ± 0.27 s 12.30 s ± 0.24 s
Number of EMs 33,220 42,659
Number of product-producing EMs (%) 8,389 (25.3%) 9,439 (22.1%)
Number of biomass-producing EMs (%) 28,336 (85.3%) 32,763 (76.8%)
Number of product- and biomass-producing EMs (%) 7,156 (21.5%) 4,427 (10.4%)
Δ G r ° Mean (kcal mol 1 ) 1.95 1.77
Δ G r ° Skewness (kcal mol 1 ) 4.54 0.42
Δ G p ° Mean (kcal mol 1 ) 111.87 88.72
Δ G p ° Median (kcal mol 1 ) 71.71 50.40
Number of thermodynamically-infeasible EMs (%) 242 (0.73%) 1487 (3.49%)
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