Figure 4
From: Stress-specific response of the p53-Mdm2 feedback loop
Effect of the mdm2 SNP309. The color map and the white dot are the same as in Figure 2B-D. In the presence of the mdm2 SNP309 G allele, the resting state of the cell is shifted towards higher k t values, as indicated by the black dot. It is not known how much the SNP changes the k t value, but the qualitative behaviour can be predicted: the same stress will lead to a weaker response for GG than for TT.