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Archived Comments for: Robust Control of PEP Formation Rate in the Carbon Fixation Pathway of C4 Plants by a Bi-functional Enzyme

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  1. At odds with published information

    James Burnell, James Cook University

    6 August 2012

    <p>The model of Hart et al., 2011 appears to be at variance with previously published material (see Burnell et al., Australian Journal of Plant Physiology 1986; 13, 203-210) which reports physiological data of PEP and pyruvate concentrations that influence PPDK activity. In addition, the model needs to be addressed in light of recent findings that the site to which ADP (as a substrate) binds and site to which ADP binds to inhibit Pi-dependent activation are the same site Astley et al., 2011 (The Plant Journal doi:10.1111/j.1365-313X.2011.04759.x.</p>

    Competing interests

    None declared