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Table 2 GO category enrichment: Biological Processes - overrepresented

From: Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

Mutant at E14.5

Mutant at E17.5

Up-regulated

Establishment or maintenance of apical/basal cell polarity

Calcium-mediated signaling

Vesicle localization

Programmed cell death

Cytosolic calcium ion transport

Negative regulation of transcription

Calcium ion transport into cytosol

Cell development

Blood vessel development

Cell motion

Vasculature development

Apoptosis

Tube development

Notch signaling pathway

Renal water transport

Cell cycle arrest

cAMP catabolic process

Transforming growth factor beta receptor signaling pathway

Fibroblast growth factor receptor signaling pathway

Regulation of cell-cell adhesion

Renal system process involved in regulation of blood volume

Kidney development

Production of nitric oxide during acute inflammatory response

Cell migration

Extracellular matrix organization

Fluid transport

Vasopressin secretion

Extracellular polysaccharide biosynthetic process

Proteolysis

Wnt receptor signaling pathway

 

Cell-cell adhesion mediated by integrin

 

Fibroblast growth factor receptor signaling pathway

Down-regulated

 

Wnt receptor signaling pathway, calcium modulating pathway

Positive regulation of cytokine secretion

Cell-cell signaling

Positive regulation of gene expression

G1/S transition of mitotic cell cycle

Positive regulation of MAP kinase activity

Carbon metabolism

Metabolic processes

Glycolysis

Cell motility

Amino acid metabolism

Developmental process

RNA splicing

DNA replication

Positive regulation of cell division

Antigen processing