Mutant at E14.5 | Mutant at E17.5 |
---|---|
Up-regulated | |
Establishment or maintenance of apical/basal cell polarity | Calcium-mediated signaling |
Vesicle localization | Programmed cell death |
Cytosolic calcium ion transport | Negative regulation of transcription |
Calcium ion transport into cytosol | Cell development |
Blood vessel development | Cell motion |
Vasculature development | Apoptosis |
Tube development | Notch signaling pathway |
Renal water transport | Cell cycle arrest |
cAMP catabolic process | Transforming growth factor beta receptor signaling pathway |
Fibroblast growth factor receptor signaling pathway | Regulation of cell-cell adhesion |
Renal system process involved in regulation of blood volume | Kidney development |
Production of nitric oxide during acute inflammatory response | Cell migration |
Extracellular matrix organization | Fluid transport |
Vasopressin secretion | Extracellular polysaccharide biosynthetic process |
Proteolysis | Wnt receptor signaling pathway |
 | Cell-cell adhesion mediated by integrin |
 | Fibroblast growth factor receptor signaling pathway |
Down-regulated | Â |
Wnt receptor signaling pathway, calcium modulating pathway | Positive regulation of cytokine secretion |
Cell-cell signaling | Positive regulation of gene expression |
G1/S transition of mitotic cell cycle | Positive regulation of MAP kinase activity |
Carbon metabolism | Metabolic processes |
Glycolysis | Cell motility |
Amino acid metabolism | Developmental process |
RNA splicing | DNA replication |
Positive regulation of cell division | Antigen processing |