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Table 4 Top 10 co-targets for countering drug resistance under INH treatment

From: Identifying co-targets to fight drug resistance based on a random walk model

Co-target Exp Essential Annotation Ref
radA 0.30 Not Essential DNA repair protein [55]
fadE10 0.19 Not Essential acyl-CoA dehydrogenase [56, 57]
Rv2165c 1.05 In Vitro essential conserved hypothetical protein [55]
echA17 0.25 Not Essential enoyl-CoA hydratase  
Rv2137c 1.32 Not Essential conserved hypothetical protein  
Ffh 0.25 In Vitro essential signal recognition particle protein [6163]
fadE14 0.12 Not Essential acyl-CoA dehydrogenase [58]
fadA 0.20 Not Essential acyl-CoA thiolase [55]
fadE12 0.15 Not Essential acyl-CoA dehydrogenase [56, 57]
cysG 0.16 In Vitro essential multifunctional siroheme synthase [64]