Figure 3
From: A strategy to study pathway cross-talks of cells under repetitive exposure to stimuli
Proposed procedure of microarray analysis for identifying candidate genes under different priming mechanism. LD: low dose stimulation; HD: high dose stimulation. Second column: Genes are grouped according to their behaviors under LD and HD, respectively. Third column: genes are further sub-grouped according to the differential expression under LD+HD or under HD alone. Genes that can only be induced by HD are further differentiated according to their regulatory behavior (e.g. activator or inhibitor) to the readout gene. Fourth column: combinations of gene from different sub-groups reveal potential priming motifs (x1 and x2 in Figure 2).