Figure 5

Individual time-series curves (blue lines) and the ensemble average (red line) of key protein concentrations for an ensemble of 1000 replicates of a IкB double gene knocked-out mutant. Computational results (left column) are compared with population-level experimental data (right column) from Ref. [20]. Panel (A): IкBβ and IкBϵ knocked-out mutant. Panel (B): IкBα and IкBβ knocked-out mutant. Panel (C): IкBα and IкBϵ knocked-out mutant.