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Table 1 Possible reactions to form pyocyanin

From: Rule–based regulatory and metabolic model for Quorum sensing in P. aeruginosa

Notation Reaction
R1 PqsE → pyocyanin
R2 C3:G3 → pyocyanin
R3 C5:G3 → pyocyanin
R4 PqsR → pyocyanin
R5 PqsH → pyocyanin
R6 PqsA → pyocyanin
R7 PqsBCD → pyocyanin
R8 PqsR + DHQ → pyocyanin
R9 PqsH + HHQ → pyocyanin
R10 PqsH + PQS → pyocyanin
R11 PqsH + DHQ → pyocyanin
R12 PqsA + HHQ → pyocyanin
R13 PqsA + PQS → pyocyanin
R14 PqsA + DHQ → pyocyanin
R15 PqsBCD + HHQ → pyocyanin
R16 PqsBCD + PQS → pyocyanin
R17 PqsBCD + DHQ → pyocyanin
R18 PqsE + HHQ → pyocyanin
R19 PqsE + PQS → pyocyanin
R20 PqsE + DHQ → pyocyanin
R21 PqsR + PqsE + HHQ → pyocyanin
R22 PqsR + PqsE + PQS → pyocyanin
R23 PqsR + PqsE + DHQ → pyocyanin
R24 PqsR + PqsE → pyocyanin
  1. Pyocyanin is positively regulated by PqsE (and therefore also PqsR) in reactions labeled as underlined, by PqsA and PqsBCD (and therefore also PqsR) in reactions labeled in bold, as well as by both in reactions labeled in italic.