Table 2 Behavior of updated networks
From: Rule–based regulatory and metabolic model for Quorum sensing in P. aeruginosa
Network | Used reactions | Results | |||
|---|---|---|---|---|---|
PqsA−– PqsBCD− | PqsE− | PqsR antagonists | PqsBCD inhibitors | ||
N1 | R1, R2 | - - - - - | Pyocyanin | Pyocyanin | - - - - - |
N2 | R18 | - - - - - | - - - - - | Pyocyanin | - - - - - |
N3 | R19 | - - - - - | - - - - - | Pyocyanin | PQS |
N4 | R20, R2 | - - - - - | Pyocyanin | Pyocyanin | - - - - - |
N5 | R1, R2, R4 | Pyocyanin | Pyocyanin | Pyocyanin | - - - - - |
N6 | R18, R4 | Pyocyanin | Pyocyanin | Pyocyanin | - - - - - |
N7 | R19, R4 | Pyocyanin | Pyocyanin | Pyocyanin | PQS |
N8 | R20, R2, R4 | Pyocyanin | Pyocyanin | Pyocyanin | - - - - - |
N9 | R21 | - - - - - | - - - - - | - - - - - | - - - - - |
N10 | R22 | - - - - - | - - - - - | - - - - - | PQS |
N11 | R23, R2 | - - - - - | Pyocyanin | Pyocyanin | - - - - - |
N12 | R24, R2 | - - - - - | Pyocyanin | Pyocyanin | - - - - - |