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Table 3 Comparison of experimental aerobic glucose-limited chemostat growth data with EcoCyc–18.0–GEM and iJO1366 constraint-based model predictions

From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database

Aerobic fluxes Experimental EcoCyc iJO1366
Specific growth rate (µ) (1/hr) 0.300 0.272 0.288
Glucose uptake (m mmol/g CDW /hr) 3.008 3.008 3.008
O 2 uptake 7.413 6.158 5.703
NH 4 uptake 2.367 2.899 3.021
Sulfate uptake   0.067 0.073
Phosphate uptake   0.260 0.267
CO 2 production 7.38 6.850 6.288
H 2O production   13.926 13.704
H + production   2.454 2.552
  1. Metabolite uptake and production rates are in units of mmol/gCDW/hr. Growth is in units of hr -1. Experimental data from Kayser et al.[23].