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Table 3 Comparison of experimental aerobic glucose-limited chemostat growth data with EcoCyc–18.0–GEM and iJO1366 constraint-based model predictions

From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database

Aerobic fluxes

Experimental

EcoCyc

iJO1366

Specific growth rate (µ) (1/hr)

0.300

0.272

0.288

Glucose uptake (m mmol/g CDW /hr)

3.008

3.008

3.008

O 2 uptake

7.413

6.158

5.703

NH 4 uptake

2.367

2.899

3.021

Sulfate uptake

 

0.067

0.073

Phosphate uptake

 

0.260

0.267

CO 2 production

7.38

6.850

6.288

H 2O production

 

13.926

13.704

H + production

 

2.454

2.552

  1. Metabolite uptake and production rates are in units of mmol/gCDW/hr. Growth is in units of hr -1. Experimental data from Kayser et al.[23].
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BMC Systems Biology

ISSN: 1752-0509

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