Figure 5

The expression profile of Smad7 in primary and secondary infection. Upon comparing the time course of Smad7 expression between the primary and secondary infection, it is clear that Smad7 expression remained stable in primary infection. During secondary infection, however, the level of Smad7 expression increased significantly by an average of 14%. This difference suggests that Smad7 may play a key role in the control of innate and adaptive immune responses.