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Table 3 Proteins identified in the zebrafish intracellular PPI network for primary infection and secondary infection are ranked by betweenness centrality

From: The role of TGF-β signaling and apoptosis in innate and adaptive immunity in zebrafish: a systems biology approach

 

Primary infection

Secondary infection

Rank

Zebrafish protein

Betweenness centrality

Degree

Zebrafish protein

Betweenness centrality

Degree

1

Elavl1

6048.44

9

Psmd1

16588.53

16

2

Zgc:63606

5972.60

5

Creb1

15020.0

5

3

Btg2

5092.00

9

Psme3

14903.00

4

4

Zgc:153257

5016.00

2

Tp53

14670.00

2

5

Fkbp5

4542.00

9

Cebpb

14334.60

6

6

Hug

4353.72

10

Mdm2

13140.00

3

7

Cul1a

3992.00

3

Casp3a

13080.00

6

8

Hsp90a.1

3642.00

10

Dhfr

13032.00

2

9

LOC563808

3641.05

5

Hspd1

12922.00

2

10

Esr1

2856.00

2

Bcl2

12612.34

4