Fig. 3
From: Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching
TGF-β receptor signalling system. a The schematic semi-reduced model, TGF-β signal transduction. TGF and \({\hat {\text {S}}}\) + 3 (S)3 represent the input and the output of the model. b A Simplified Model of TGF-β signal transduction. TGF-β and \(\hat {\text {S}}+ \text {S}_{\text {n}} + 3 \text {(S)}_{\text {3}}\) represent the input and the output of the model. Both positive and negative feedback loops are indicated by dot-ended solid lines emerging from (S)3. τ P and τ N represent time-delays incorporated in the positive and negative feedback loops, respectively