Volume 10 Supplement 1

Selected articles from the Fourteenth Asia Pacific Bioinformatics Conference (APBC 2016): Systems Biology


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process. The Supplement Editors declare that they have no competing interests.

San Francisco, CA, USA

11 - 13 January 2016

Edited by Jijun Tang, Lu Tian and Yi-Ping Phoebe Chen.

Related articles have been published in supplements to BMC Bioinformatics and BMC Genomics.

  1. Proceedings

    c-Myc and viral cofactor Kaposin B co-operate to elicit angiogenesis through modulating miRNome traits of endothelial cells

    MicroRNAs (miRNAs) have emerged as master regulators of angiogenesis and other cancer-related events. Discovering new angiogenesis-regulating microRNAs (angiomiRs) will eventually help in developing new therap...

    Hsin-Chuan Chang, Tsung-Han Hsieh, Yi-Wei Lee, Cheng-Fong Tsai, Ya-Ni Tsai, Cheng-Chung Cheng and Hsei-Wei Wang

    BMC Systems Biology 2016 10(Suppl 1):S1

    Published on: 11 January 2016

  2. Proceedings

    Prediction of drugs having opposite effects on disease genes in a directed network

    Developing novel uses of approved drugs, called drug repositioning, can reduce costs and times in traditional drug development. Network-based approaches have presented promising results in this field. However,...

    Hasun Yu, Sungji Choo, Junseok Park, Jinmyung Jung, Yeeok Kang and Doheon Lee

    BMC Systems Biology 2016 10(Suppl 1):S2

    Published on: 11 January 2016

  3. Proceedings

    UbiSite: incorporating two-layered machine learning method with substrate motifs to predict ubiquitin-conjugation site on lysines

    The conjugation of ubiquitin to a substrate protein (protein ubiquitylation), which involves a sequential process – E1 activation, E2 conjugation and E3 ligation, is crucial to the regulation of protein functi...

    Chien-Hsun Huang, Min-Gang Su, Hui-Ju Kao, Jhih-Hua Jhong, Shun-Long Weng and Tzong-Yi Lee

    BMC Systems Biology 2016 10(Suppl 1):S6

    Published on: 11 January 2016


    Generalized logical model based on network topology to capture the dynamical trends of cellular signaling pathways

    Cellular responses to extracellular perturbations require signaling pathways to capture and transmit the signals. However, the underlying molecular mechanisms of signal transduction are not yet fully understoo...

    Fan Zhang, Haoting Chen, Li Na Zhao, Hui Liu, Teresa M. Przytycka and Jie Zheng

    BMC Systems Biology 2016 10(Suppl 1):S7

    Published on: 11 January 2016

  5. Proceedings

    Meta-analysis of sex differences in gene expression in schizophrenia

    Schizophrenia is a severe psychiatric disorder which influences around 1 % of the worldwide population. Differences between male and female patients with schizophrenia have been noted. There is an earlier age ...

    Wenyi Qin, Cong Liu, Monsheel Sodhi and Hui Lu

    BMC Systems Biology 2016 10(Suppl 1):S9

    Published on: 11 January 2016