Skip to content

Advertisement

You're viewing the new version of our site. Please leave us feedback.

Learn more

BMC Systems Biology

Volume 6 Supplement 2

Proceedings of the 23rd International Conference on Genome Informatics (GIW 2012)

Proceedings

Edited by Jung-Hsien Chiang, Tien-Hao Chang and Hung-Yu Kao

This supplement has not been supported by sponsorship or other external funding.

23rd International Conference on Genome Informatics (GIW 2012). Go to conference site.

Tainan, Taiwan12-14 December 2012

  1. Content type: Proceedings

    Pathway data are important for understanding the relationship between genes, proteins and many other molecules in living organisms. Pathway gene relationships are crucial information for guidance, prediction, ...

    Authors: Hufeng Zhou, Jingjing Jin, Haojun Zhang, Bo Yi, Michal Wozniak and Limsoon Wong

    Citation: BMC Systems Biology 2012 6(Suppl 2):S2

    Published on:

  2. Content type: Proceedings

    One important application of microarray in clinical settings is for constructing a diagnosis or prognosis model. Batch effects are a well-known obstacle in this type of applications. Recently, a prominent stud...

    Authors: Chuan Hock Koh and Limsoon Wong

    Citation: BMC Systems Biology 2012 6(Suppl 2):S3

    Published on:

  3. Content type: Proceedings

    The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery i...

    Authors: Xin Chen, Qiong Wu, Ruimin Sun and Louxin Zhang

    Citation: BMC Systems Biology 2012 6(Suppl 2):S5

    Published on:

  4. Content type: Proceedings

    Hot spots are residues contributing the most of binding free energy yet accounting for a small portion of a protein interface. Experimental approaches to identify hot spots such as alanine scanning mutagenesis...

    Authors: Bin Xu, Xiaoming Wei, Lei Deng, Jihong Guan and Shuigeng Zhou

    Citation: BMC Systems Biology 2012 6(Suppl 2):S6

    Published on:

  5. Content type: Proceedings

    Proteins interact with other proteins or biomolecules in complexes to perform cellular functions. Existing protein-protein interaction (PPI) databases and protein complex databases for human proteins are not o...

    Authors: Shingo Kikugawa, Kensaku Nishikata, Katsuhiko Murakami, Yoshiharu Sato, Mami Suzuki, Md Altaf-Ul-Amin, Shigehiko Kanaya and Tadashi Imanishi

    Citation: BMC Systems Biology 2012 6(Suppl 2):S7

    Published on:

  6. Content type: Proceedings

    Due to the difficulty in separating two (paternal and maternal) copies of a chromosome, most published human genome sequences only provide genotype information, i.e., the mixed information of the underlying two h...

    Authors: Minzhu Xie, Jianxin Wang and Tao Jiang

    Citation: BMC Systems Biology 2012 6(Suppl 2):S8

    Published on:

  7. Content type: Proceedings

    Current next-generation sequencing (NGS) platforms adopt two types of sequencing mechanisms: by synthesis or by ligation. The former is employed by 454 and Solexa systems, while the latter by SOLiD system. Alt...

    Authors: Yu-Feng Huang, Sheng-Chung Chen, Yih-Shien Chiang, Tzu-Han Chen and Kuo-Ping Chiu

    Citation: BMC Systems Biology 2012 6(Suppl 2):S10

    Published on:

  8. Content type: Proceedings

    TNF (Tumor Necrosis Factor-α) induces HUVEC (Human Umbilical Vein Endothelial Cells) to proliferate and form new blood vessels. This TNF-induced angiogenesis plays a key role in cancer and rheumatic disease. H...

    Authors: Kentaro Ogami, Rui Yamaguchi, Seiya Imoto, Yoshinori Tamada, Hiromitsu Araki, Cristin Print and Satoru Miyano

    Citation: BMC Systems Biology 2012 6(Suppl 2):S12

    Published on:

  9. Content type: Proceedings

    Protein complexes participate in many important cellular functions, so finding the set of existent complexes is essential for understanding the organization and regulation of processes in the cell. With the av...

    Authors: Chern Han Yong, Guimei Liu, Hon Nian Chua and Limsoon Wong

    Citation: BMC Systems Biology 2012 6(Suppl 2):S13

    Published on:

  10. Content type: Proceedings

    The expression of microRNA (miRNA) genes undergoes several maturation steps. Recent studies brought new insights into the maturation process, but also raised debates on the maturation mechanism. To understand ...

    Authors: Sung-Chou Li, Kuo-Wang Tsai, Hung-Wei Pan, Yung-Ming Jeng, Meng-Ru Ho and Wen-Hsiung Li

    Citation: BMC Systems Biology 2012 6(Suppl 2):S14

    Published on:

  11. Content type: Proceedings

    Transcriptional networks of higher eukaryotes are difficult to obtain. Available experimental data from conventional approaches are sporadic, while those generated with modern high-throughput technologies are ...

    Authors: Martin Haubrock, Jie Li and Edgar Wingender

    Citation: BMC Systems Biology 2012 6(Suppl 2):S15

    Published on: