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Volume 6 Supplement 3

The International Conference on Intelligent Biology and Medicine (ICIBM): Systems Biology


Edited by Zhongming Zhao, Bing Zhang, Yufei Huang, Hua Xu and Yu Shyr

The conference was supported by a grant from National Science Foundation, USA (1141979) and financial support from the Center for Quantitative Sciences, Vanderbilt University. There was no sponsorship or other external funding for publication of the supplement.

The International Conference on Intelligent Biology and Medicine (ICIBM). Go to conference site.

Nashville, TN, USA22-24 April 2012

  1. Content type: Introduction

    The 2012 International Conference on Intelligent Biology and Medicine (ICIBM 2012) was held on April 22-24, 2012 in Nashville, Tennessee, USA. The conference featured six technical sessions, one tutorial sessi...

    Authors: Yufei Huang, Zhongming Zhao, Hua Xu, Yu Shyr and Bing Zhang

    Citation: BMC Systems Biology 2012 6(Suppl 3):S1

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  2. Content type: Research

    Despite large amounts of available genomic and proteomic data, predicting the structure and response of signaling networks is still a significant challenge. While statistical method such as Bayesian network ha...

    Authors: Tingting Qin, Lam C Tsoi, Kellie J Sims, Xinghua Lu and W Jim Zheng

    Citation: BMC Systems Biology 2012 6(Suppl 3):S3

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  3. Content type: Research

    Malaria causes over one million deaths annually, posing an enormous health and economic burden in endemic regions. The completion of genome sequencing of the causative agents, a group of parasites in the genus Pl...

    Authors: Hong Cai, Changjin Hong, Jianying Gu, Timothy G Lilburn, Rui Kuang and Yufeng Wang

    Citation: BMC Systems Biology 2012 6(Suppl 3):S5

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  4. Content type: Research

    Contemporary high-throughput analyses often produce lengthy lists of genes or proteins. It is desirable to divide the genes into functionally coherent subsets for further investigation, by integrating heteroge...

    Authors: Adam J Richards, John H Schwacke, Bärbel Rohrer, L Ashley Cowart and Xinghua Lu

    Citation: BMC Systems Biology 2012 6(Suppl 3):S7

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  5. Content type: Research

    Cardiac aging is characterized by diastolic dysfunction of the left ventricle (LV), which is due in part to increased LV wall stiffness. In the diastolic phase, myocytes are relaxed and extracellular matrix (E...

    Authors: Tianyi Yang, Ying Ann Chiao, Yunji Wang, Andrew Voorhees, Hai-Chao Han, Merry L Lindsey and Yu-Fang Jin

    Citation: BMC Systems Biology 2012 6(Suppl 3):S10

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  6. Content type: Research

    Bacterial 16S Ribosomal RNAs profiling have been widely used in the classification of microbiota associated diseases. Dimensionality reduction is among the keys in mining high-dimensional 16S rRNAs' expression...

    Authors: Yin Wang, Yuhua Zhou, Yixue Li, Zongxin Ling, Yan Zhu, Xiaokui Guo and Hong Sun

    Citation: BMC Systems Biology 2012 6(Suppl 3):S12

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  7. Content type: Research

    Pathway analysis of large-scale omics data assists us with the examination of the cumulative effects of multiple functionally related genes, which are difficult to detect using the traditional single gene/marker ...

    Authors: Peilin Jia, Yang Liu and Zhongming Zhao

    Citation: BMC Systems Biology 2012 6(Suppl 3):S13

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  8. Content type: Research

    Detecting epistatic interactions plays a significant role in improving pathogenesis, prevention, diagnosis, and treatment of complex human diseases. Applying machine learning or statistical methods to epistati...

    Authors: Bing Han, Xue-wen Chen, Zohreh Talebizadeh and Hua Xu

    Citation: BMC Systems Biology 2012 6(Suppl 3):S14

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  9. Content type: Research

    Interactions among genomic loci (also known as epistasis) have been suggested as one of the potential sources of missing heritability in single locus analysis of genome-wide association studies (GWAS). The com...

    Authors: Yu Liu, Sean Maxwell, Tao Feng, Xiaofeng Zhu, Robert C Elston, Mehmet Koyutürk and Mark R Chance

    Citation: BMC Systems Biology 2012 6(Suppl 3):S15

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  10. Content type: Research

    Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. Studies have correlated risk of CRC development with dietary habits and environmental conditions. Gene signatures for any diseas...

    Authors: Meeta P Pradhan, Kshithija Nagulapalli and Mathew J Palakal

    Citation: BMC Systems Biology 2012 6(Suppl 3):S17

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  11. Content type: Research

    Animal models are indispensable tools in studying the cause of human diseases and searching for the treatments. The scientific value of an animal model depends on the accurate mimicry of human diseases. The pr...

    Authors: Shuhao Yu, Lulu Zheng, Yun Li, Chunyan Li, Chenchen Ma, Yixue Li, Xuan Li and Pei Hao

    Citation: BMC Systems Biology 2012 6(Suppl 3):S18

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  12. Content type: Research

    Central precocious puberty (CPP) is a common pediatric endocrine disease caused by early activation of hypothalamic-putuitary-gonadal (HPG) axis, yet the exact mechanism was poorly understood. Although there w...

    Authors: Linlin Yang, Kailin Tang, Ying Qi, Hao Ye, Wenlian Chen, Yongyu Zhang and Zhiwei Cao

    Citation: BMC Systems Biology 2012 6(Suppl 3):S19

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  13. Content type: Research

    One of the primary challenges in translational research data management is breaking down the barriers between the multiple data silos and the integration of 'omics data with clinical information to complete th...

    Authors: Catherine P Jayapandian, Meng Zhao, Rob M Ewing, Guo-Qiang Zhang and Satya S Sahoo

    Citation: BMC Systems Biology 2012 6(Suppl 3):S20

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  14. Content type: Research

    Sequencing of bacterial genomes became an essential approach to study pathogen virulence and the phylogenetic relationship among close related strains. Bacterium Enterococcus faecium emerged as an important nosoc...

    Authors: Yajun Wang, Yao Yu, Bohu Pan, Pei Hao, Yixue Li, Zhifeng Shao, Xiaogang Xu and Xuan Li

    Citation: BMC Systems Biology 2012 6(Suppl 3):S21

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  15. Content type: Research

    Typical analysis of time-series gene expression data such as clustering or graphical models cannot distinguish between early and later drug responsive gene targets in cancer cells. However, these genes would r...

    Authors: Pengyue Zhang, Raphaël Mourad, Yang Xiang, Kun Huang, Tim Huang, Kenneth Nephew, Yunlong Liu and Lang Li

    Citation: BMC Systems Biology 2012 6(Suppl 3):S9

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2017 Journal Metrics

  • Citation Impact
    2.05 - 2-year Impact Factor
    2.505 - 5-year Impact Factor
    0.689 - Source Normalized Impact per Paper (SNIP)
    1.109 - SCImago Journal Rank (SJR)


    Social Media Impact
    523 mentions