The hardware accelerators will provide solutions to computationally complex problems in bioinformatics fields. However, the effect of acceleration depends on the nature of the application, thus selection of an...
Volume 9 Supplement 1
Selected articles from the Thirteenth Asia Pacific Bioinformatics Conference (APBC 2015): Systems Biology
Edited by Yi-Ping Phoebe Chen and Hsien-Da Huang
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process. The Supplement Editors declare that they have no competing interests.
The Thirteenth Asia Pacific Bioinformatics Conference (APBC 2015). Go to conference site.
HsinChu, Taiwan21-23 January 2015
Citation: BMC Systems Biology 2015 9(Suppl 1):S6
Identifying DNA-binding proteins by combining support vector machine and PSSM distance transformation
DNA-binding proteins play a pivotal role in various intra- and extra-cellular activities ranging from DNA replication to gene expression control. Identification of DNA-binding proteins is one of the major chal...Citation: BMC Systems Biology 2015 9(Suppl 1):S10
cisPath: an R/Bioconductor package for cloud users for visualization and management of functional protein interaction networks
With the burgeoning development of cloud technology and services, there are an increasing number of users who prefer cloud to run their applications. All software and associated data are hosted on the cloud, a...Citation: BMC Systems Biology 2015 9(Suppl 1):S1
Cell proliferation, differentiation, Gene expression, metabolism, immunization and signal transduction require the participation of ligands and targets. It is a great challenge to identify rules governing mole...Citation: BMC Systems Biology 2015 9(Suppl 1):S2
High throughput techniques produce multiple functional association networks. Integrating these networks can enhance the accuracy of protein function prediction. Many algorithms have been introduced to generate...Citation: BMC Systems Biology 2015 9(Suppl 1):S3
Computational cell fate modelling for discovery of rewiring in apoptotic network for enhanced cancer drug sensitivity
The ongoing cancer research has shown that malignant tumour cells have highly disrupted signalling transduction pathways. In cancer cells, signalling pathways are altered to satisfy the demands of continuous p...Citation: BMC Systems Biology 2015 9(Suppl 1):S4
Transcription factor and microRNA-regulated network motifs for cancer and signal transduction networks
Molecular networks are the basis of biological processes. Such networks can be decomposed into smaller modules, also known as network motifs. These motifs show interesting dynamical behaviors, in which co-oper...Citation: BMC Systems Biology 2015 9(Suppl 1):S5
Comparative network analysis can provide an effective means of analyzing large-scale biological networks and gaining novel insights into their structure and organization. Global network alignment aims to predi...Citation: BMC Systems Biology 2015 9(Suppl 1):S7
Investigating the utility of clinical outcome-guided mutual information network in network-based Cox regression
Network-based approaches have recently gained considerable popularity in high- dimensional regression settings. For example, the Cox regression model is widely used in expression analysis to predict the surviv...Citation: BMC Systems Biology 2015 9(Suppl 1):S8
Protein functional properties prediction in sparsely-label PPI networks through regularized non-negative matrix factorization
Predicting functional properties of proteins in protein-protein interaction (PPI) networks presents a challenging problem and has important implication in computational biology. Collective classification (CC) ...Citation: BMC Systems Biology 2015 9(Suppl 1):S9