New tools for self-organized pattern formation
© Bernhardt et al; licensee BioMed Central Ltd. 2007
Published: 8 May 2007
Multicellular organisms undergo self-organisation during development. Our aim was to engineer self-organised pattern formation in free-swimming bacteria cells by providing an artificial system for bi-directional communication. E. coli cells would be equipped with genes derived from independent quorum sensing systems from P. aeruginosa and V. fischeri. These systems enable communication between cell populations and can enable regulated switching between competing cell fates. The negotiation of cell fates within bacterial populations can be visualized precisely by the expression of different fluorescent proteins.
Experiments conducted and results obtained
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