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BMC Systems Biology

Volume 4 Supplement 2

Selected articles from the Third International Symposium on Optimization and Systems Biology

Proceedings

Edited by Luonan Chen, Xiang-Sun Zhang and Yong Wang

Optimization and Systems Biology. Go to conference site.

Zhangjiajie, China20 - 22 September 2009

  1. Content type: Meeting report

    A report of the 3nd International Symposium on Optimization and Systems Biology, 20-22 September 2009, Zhangjiajie, China.

    Authors: Yong Wang, Xiang-Sun Zhang and Luonan Chen

    Citation: BMC Systems Biology 2010 4(Suppl 2):S1

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  2. Content type: Proceedings

    Transcription factors (TFs) regulate downstream genes in response to environmental stresses in plants. Identification of TF target genes can provide insight on molecular mechanisms of stress response systems, ...

    Authors: Gyan Prakash Srivastava, Ping Li, Jingdong Liu and Dong Xu

    Citation: BMC Systems Biology 2010 4(Suppl 2):S2

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  3. Content type: Proceedings

    Post-genome era brings about diverse categories of omics data. Inference and analysis of genetic regulatory networks act prominently in extracting inherent mechanisms, discovering and interpreting the related ...

    Authors: Binhua Tang, Xuechen Wu, Ge Tan, Su-Shing Chen, Qing Jing and Bairong Shen

    Citation: BMC Systems Biology 2010 4(Suppl 2):S3

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  4. Content type: Proceedings

    Predicting drug-protein interactions from heterogeneous biological data sources is a key step for in silico drug discovery. The difficulty of this prediction task lies in the rarity of known drug-protein interact...

    Authors: Zheng Xia, Ling-Yun Wu, Xiaobo Zhou and Stephen TC Wong

    Citation: BMC Systems Biology 2010 4(Suppl 2):S6

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  5. Content type: Proceedings

    Complex diseases, such as Type 2 Diabetes, are generally caused by multiple factors, which hamper effective drug discovery. To combat these diseases, combination regimens or combination drugs provide an altern...

    Authors: Zikai Wu, Xing-Ming Zhao and Luonan Chen

    Citation: BMC Systems Biology 2010 4(Suppl 2):S7

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  6. Content type: Proceedings

    The eosinophil cationic protein (ECP) is cytotoxic to bacteria, viruses, parasites and mammalian cells. Cells are damaged via processes of pore formation, permeability alteration and membrane leaking. Some clinic...

    Authors: Hao-Teng Chang, Louis J Tseng, Ta-Jen Hung, Blacky T Kao, Wei-Yong Lin, Tan-chi Fan, Margaret Dah-Tsyr Chang and Tun-Wen Pai

    Citation: BMC Systems Biology 2010 4(Suppl 2):S8

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  7. Content type: Proceedings

    The investigation of network dynamics is a major issue in systems and synthetic biology. One of the essential steps in a dynamics investigation is the parameter estimation in the model that expresses biologica...

    Authors: Masahiko Nakatsui, Katsuhisa Horimoto, Masahiro Okamoto, Yasuhito Tokumoto and Jun Miyake

    Citation: BMC Systems Biology 2010 4(Suppl 2):S9

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  8. Content type: Proceedings

    With ever increasing amount of available data on biological networks, modeling and understanding the structure of these large networks is an important problem with profound biological implications. Cellular fu...

    Authors: Shihua Zhang, Xue-Mei Ning, Chris Ding and Xiang-Sun Zhang

    Citation: BMC Systems Biology 2010 4(Suppl 2):S10

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  9. Content type: Proceedings

    Alzheimer's disease (AD) is a major neurodegenerative disorder leading to amnesia, cognitive impairment and dementia in the elderly. Usually this type of lesions results from dysfunctional protein cooperations...

    Authors: Zhi-Ping Liu, Yong Wang, Xiang-Sun Zhang and Luonan Chen

    Citation: BMC Systems Biology 2010 4(Suppl 2):S11

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  10. Content type: Proceedings

    The fungal pathogen Fusarium graminearum (telomorph Gibberella zeae) is the causal agent of several destructive crop diseases, where a set of genes usually work in concert to cause diseases to crops. To function ...

    Authors: Chenglei Sun, Xing-Ming Zhao, Weihua Tang and Luonan Chen

    Citation: BMC Systems Biology 2010 4(Suppl 2):S12

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  11. Content type: Proceedings

    Comparison of various kinds of biological data is one of the main problems in bioinformatics and systems biology. Data compression methods have been applied to comparison of large sequence data and protein str...

    Authors: Morihiro Hayashida and Tatsuya Akutsu

    Citation: BMC Systems Biology 2010 4(Suppl 2):S13

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