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Volume 5 Supplement 2

22nd International Conference on Genome Informatics: Systems Biology

Proceedings

Edited by Doheon Lee, Xuegong Zhang, and KiYoung Lee

22nd International Conference on Genome Informatics. Go to conference site.

Busan, Korea5-7 December 2011

  1. Microarray analyses based on differentially expressed genes (DEGs) have been widely used to distinguish samples across different cellular conditions. However, studies based on DEGs have not been able to clearl...

    Authors: Dukyong Yoon, Hyosil Kim, Haeyoung Suh-Kim, Rae Woong Park and KiYoung Lee
    Citation: BMC Systems Biology 2011 5(Suppl 2):S1
  2. Deficiency of the transcription factor MafB, which is normally expressed in macrophages, can underlie cellular dysfunction associated with a range of autoimmune diseases and arteriosclerosis. MafB has importan...

    Authors: Mariko Morita, Megumi Nakamura, Michito Hamada and Satoru Takahashi
    Citation: BMC Systems Biology 2011 5(Suppl 2):S7
  3. In recent years, a number of tools have been developed to explore microRNAs (miRNAs) by analyzing their target genes. However, a reverse problem, that is, inferring patterns of protein-coding genes through the...

    Authors: Chengxiang Qiu, Juan Wang and Qinghua Cui
    Citation: BMC Systems Biology 2011 5(Suppl 2):S9
  4. To understand how stroke risk factors mechanistically contribute to stroke, the genetic components regulating each risk factor need to be integrated and evaluated with respect to biological function and throug...

    Authors: Young-Kyu Park, Ok Sun Bang, Min-Ho Cha, Jaeheup Kim, John W Cole, Doheon Lee and Young Joo Kim
    Citation: BMC Systems Biology 2011 5(Suppl 2):S10
  5. The current genome-wide association (GWA) analysis mainly focuses on the single genetic variant, which may not reveal some the genetic variants that have small individual effects but large joint effects. Consi...

    Authors: Jaehoon Lee, Soyeon Ahn, Sohee Oh, Bruce Weir and Taesung Park
    Citation: BMC Systems Biology 2011 5(Suppl 2):S11
  6. Current Genome-Wide Association Studies (GWAS) are performed in a single trait framework without considering genetic correlations between important disease traits. Hence, the GWAS have limitations in discoveri...

    Authors: Sung Hee Park, Ji Young Lee and Sangsoo Kim
    Citation: BMC Systems Biology 2011 5(Suppl 2):S13
  7. Genome-scale metabolic network models have contributed to elucidating biological phenomena, and predicting gene targets to engineer for biotechnological applications. With their increasing importance, their pr...

    Authors: Hyun Uk Kim, Tae Yong Kim and Sang Yup Lee
    Citation: BMC Systems Biology 2011 5(Suppl 2):S14
  8. The increasing availability of time series microbial community data from metagenomics and other molecular biological studies has enabled the analysis of large-scale microbial co-occurrence and association netw...

    Authors: Li C Xia, Joshua A Steele, Jacob A Cram, Zoe G Cardon, Sheri L Simmons, Joseph J Vallino, Jed A Fuhrman and Fengzhu Sun
    Citation: BMC Systems Biology 2011 5(Suppl 2):S15