McGuire WL: Prognostic factors for recurrence and survival in human breast cancer. Breast Cancer Research and Treatment. 1987, 10: 5-9. 10.1007/BF01806129.
Article
CAS
PubMed
Google Scholar
Foster RS: The biologic and clinical significance of lymphatic metastases in breast cancer. Surgical oncology clinics of North America. 1996, 5: 79-
PubMed
Google Scholar
Christine LC, Carol A, Donald EH: Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases. Cancer. 1989, 63: 181-187. 10.1002/1097-0142(19890101)63:1<181::AID-CNCR2820630129>3.0.CO;2-H.
Article
Google Scholar
Fidler IJ: THE PATHOGENESIS OF CANCER METASTASIS: THE 'SEED AND SOIL' HYPOTHESIS REVISITED. Nature Reviews Cancer. 2003, 3: 453-458. 10.1038/nrc1098.
Article
CAS
PubMed
Google Scholar
Gupta GP, Massague J: Cancer Metastasis: Building a Framework. Cell. 2006, 127: 679-695. 10.1016/j.cell.2006.11.001.
Article
CAS
PubMed
Google Scholar
Nguyen DX, Massague J: Genetic determinants of cancer metastasis. Nat Rev Genet. 2007, 8: 341-352.
Article
CAS
PubMed
Google Scholar
Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K: Metastasis: Lymphangiogenesis and cancer metastasis. Nat Rev Cancer. 2002, 2: 573-583. 10.1038/nrc863.
Article
CAS
PubMed
Google Scholar
Jatoi I, Hilsenbeck SG, Clark GM, Osborne CK: Significance of Axillary Lymph Node Metastasis in Primary Breast Cancer. J Clin Oncol. 1999, 17: 2334-2340.
CAS
PubMed
Google Scholar
Nasser IA, Lee AK, Bosari S, Saganich R, Heatley G, Silverman ML: Occult axillary lymph node metastases in node-negative breast carcinoma. Human pathology. 1993, 24: 950-10.1016/0046-8177(93)90108-S.
Article
CAS
PubMed
Google Scholar
Gasparini G, Weidner N, Bevilacqua P, Maluta S, Dalla Palma P, Caffo O, Barbareschi M, Boracchi P, Marubini E, Pozza F: Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node- negative breast carcinoma. J Clin Oncol. 1994, 12: 454-466.
CAS
PubMed
Google Scholar
Sorlie T: Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA. 2001, 98: 10869-10874. 10.1073/pnas.191367098.
Article
PubMed Central
CAS
PubMed
Google Scholar
van de Vijver MJ: A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med. 2002, 347: 1999-2009. 10.1056/NEJMoa021967.
Article
CAS
PubMed
Google Scholar
van/'t Veer LJ: Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002, 415: 530-536. 10.1038/415530a.
Article
Google Scholar
Ramaswamy S, Ross KN, Lander ES, Golub TR: A molecular signature of metastasis in primary solid tumors. Nature Genet. 2003, 33: 49-54. 10.1038/ng1060.
Article
CAS
PubMed
Google Scholar
Wang Y, Klijn JGM, Zhang Y, Sieuwerts AM, Look MP, Yang F, Talantov D, Timmermans M, Meijer-van Gelder ME, Yu J, et al: Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. The Lancet. 2005, 365: 671-679.
Article
CAS
Google Scholar
Sun Y, Goodison S, Li J, Liu L, Farmerie W: Improved breast cancer prognosis through the combination of clinical and genetic markers. Bioinformatics. 2007, 23: 30-37. 10.1093/bioinformatics/btl543.
Article
PubMed Central
CAS
PubMed
Google Scholar
Suzuki M, Tarin D: Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: clinical implications. Molecular oncology. 2007, 1: 172-180. 10.1016/j.molonc.2007.03.005.
Article
PubMed
Google Scholar
Abba MC, Sun H, Hawkins KA, Drake JA, Hu Y, Nunez MI, Gaddis S, Shi T, Horvath S, Sahin A: Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status. Molecular Cancer Research. 2007, 5: 881-10.1158/1541-7786.MCR-07-0055.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ellsworth RE, Seebach J, Field LA, Heckman C, Kane J, Hooke JA, Love B, Shriver CD: A gene expression signature that defines breast cancer metastases. Clinical and Experimental Metastasis. 2009, 26: 205-213. 10.1007/s10585-008-9232-9.
Article
CAS
PubMed
Google Scholar
Singletary SE, Connolly JL: Breast Cancer Staging: Working With the Sixth Edition of the AJCC Cancer Staging Manual. CA Cancer J Clin. 2006, 56: 37-47. 10.3322/canjclin.56.1.37.
Article
PubMed
Google Scholar
Weigelt B, Wessels LFA, Bosma AJ, Glas AM, Nuyten DSA, He YD, Dai H, Peterse JL, van't Veer LJ: No common denominator for breast cancer lymph node metastasis. Br J Cancer. 2005, 93: 924-932. 10.1038/sj.bjc.6602794.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dickey DA, Fuller WA: Distribution of the estimators for autoregressive time series with a unit root. Journal of the American statistical association. 1979, 427-431.
Google Scholar
W MC: Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach. Journal of Evolutionary Biology. 2005, 18: 1368-1373. 10.1111/j.1420-9101.2005.00917.x.
Article
Google Scholar
Eden E, Navon R, Steinfeld I, Lipson D, Yakhini Z: GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinformatics. 2009, 10: 48-10.1186/1471-2105-10-48.
Article
PubMed Central
PubMed
Google Scholar
Noriaki S, Hiroyuki K, Masayuki W, Soichiro M, Masaki M, Keizo S: Local immune response to tumor invasion in esophageal squamous cell carcinoma: The expression of human leukocyte antigen-DR and lymphocyte infiltration. Cancer. 1994, 74: 586-591. 10.1002/1097-0142(19940715)74:2<586::AID-CNCR2820740209>3.0.CO;2-4.
Article
Google Scholar
de Visser KE, Eichten A, Coussens LM: Paradoxical roles of the immune system during cancer development. Nat Rev Cancer. 2006, 6: 24-37. 10.1038/nrc1782.
Article
CAS
PubMed
Google Scholar
Byrne KJO, Dalgleish AG, Browning MJ, Steward WP, Harris AL: The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease. European journal of cancer (Oxford, England : 1990). 2000, 36: 151-169. 10.1016/S0959-8049(99)00241-5.
Article
Google Scholar
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 2005, 102: 15545-15550. 10.1073/pnas.0506580102.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zou W: Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer. 2005, 5: 263-274. 10.1038/nrc1586.
Article
CAS
PubMed
Google Scholar
Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J, Harris AL: Association of Macrophage Infiltration with Angiogenesis and Prognosis in Invasive Breast Carcinoma. Cancer Res. 1996, 56: 4625-4629.
CAS
PubMed
Google Scholar
Lin EY, Pollard JW: Tumor-Associated Macrophages Press the Angiogenic Switch in Breast Cancer. Cancer Res. 2007, 67: 5064-5066. 10.1158/0008-5472.CAN-07-0912.
Article
CAS
PubMed
Google Scholar
Pollard JW: Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 2004, 4: 71-78. 10.1038/nrc1256.
Article
CAS
PubMed
Google Scholar
DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM: CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages. Cancer Cell. 2009, 16: 91-102. 10.1016/j.ccr.2009.06.018.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi J-T, Rijn Mvd, Botstein D, Brown PO: Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds. PLoS Biol. 2004, 2: e7-10.1371/journal.pbio.0020007.
Article
PubMed Central
PubMed
Google Scholar
Zambelli F, Pesole G, Pavesi G: Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes. Nucl Acids Res. 2009, 37: W247-252. 10.1093/nar/gkp464.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dennis G, Sherman B, Hosack D, Yang J, Gao W, Lane HC, Lempicki R: DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biology. 2003, 4: P3-10.1186/gb-2003-4-5-p3.
Article
PubMed
Google Scholar
Huang DW, Sherman BT, Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protocols. 2008, 4: 44-57. 10.1038/nprot.2008.211.
Article
Google Scholar
Vlieghe D, Sandelin A, De Bleser PJ, Vleminckx K, Wasserman WW, van Roy F, Lenhard B: A new generation of JASPAR, the open-access repository for transcription factor binding site profiles. Nucl Acids Res. 2006, 34: D95-97. 10.1093/nar/gkj115.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dalton S, Treisman R: Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell. 1992, 68: 597-612. 10.1016/0092-8674(92)90194-H.
Article
CAS
PubMed
Google Scholar
Wang Y, Liu D-P, Chen P-P, Koeffler HP, Tong X-J, Xie D: Involvement of IFN Regulatory Factor (IRF)-1 and IRF-2 in the Formation and Progression of Human Esophageal Cancers. Cancer Res. 2007, 67: 2535-2543. 10.1158/0008-5472.CAN-06-3530.
Article
CAS
PubMed
Google Scholar
Huang Suyun, B CD, Van Arsdall Melissa, Fidler Isaiah J: Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene. 2002, 21: 2504-2512. 10.1038/sj.onc.1205341.
Article
CAS
PubMed
Google Scholar
Khodarev NN, Roach P, Pitroda SP, Golden DW, Bhayani M, Shao MY, Darga TE, Beveridge MG, Sood RF, Sutton HG, et al: STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy. PLoS ONE. 2009, 4: e5821-10.1371/journal.pone.0005821.
Article
PubMed Central
PubMed
Google Scholar
Woelfle U, Assmann V, Pantel K: Conditionally active STAT1 and its functional role in tumor progression and invasion. AACR Meeting Abstracts. 2006, 2006: 430-a-.
Google Scholar
Yu H, Pardoll D, Jove R: STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer. 2009, 9: 798-809. 10.1038/nrc2734.
Article
CAS
PubMed
Google Scholar
Richardson AL, Wang ZC, De Nicolo A, Lu X, Brown M, Miron A, Liao X, Iglehart JD, Livingston DM, Ganesan S: X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell. 2006, 9: 121-132. 10.1016/j.ccr.2006.01.013.
Article
CAS
PubMed
Google Scholar
Wilson CL, Miller CJ: Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis. Bioinformatics. 2005, 21: 3683-3685. 10.1093/bioinformatics/bti605.
Article
CAS
PubMed
Google Scholar
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM: ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia. 2004, 6: 1-6.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fisher RA: Statistical methods for research workers Edinburgh. Oliver and Boyd. 1950, 354:
Google Scholar
Stouffer SA, DeVinney LC, Suchmen EA: The American soldier: Adjustment during army life. 1949, Princeton University Press Princeton, NJ
Google Scholar
Hong F, Breitling R: A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments. Bioinformatics. 2008, 24: 374-382. 10.1093/bioinformatics/btm620.
Article
CAS
PubMed
Google Scholar