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Volume 6 Supplement 1

Selected articles from The 5th IEEE International Conference on Systems Biology (ISB 2011)


Edited by Luonan Chen, Xiang-Sun Zhang and Yong Wang

The 5th IEEE International Conference on Computational Systems Biology (ISB 2011). Go to conference site.

Zhuhai, China02-04 September 2011

  1. We have recently identified a number of active regulatory networks involved in diabetes progression in Goto-Kakizaki (GK) rats by network screening. The networks were quite consistent with the previous knowled...

    Authors: Guanying Piao, Shigeru Saito, Yidan Sun, Zhi-Ping Liu, Yong Wang, Xiao Han, Jiarui Wu, Huarong Zhou, Luonan Chen and Katsuhisa Horimoto
    Citation: BMC Systems Biology 2012 6(Suppl 1):S2
  2. Combination of different agents is widely used in clinic to combat complex diseases with improved therapy and reduced side effects. However, the identification of effective drug combinations remains a challeng...

    Authors: Ke-Jia Xu, Jiangning Song and Xing-Ming Zhao
    Citation: BMC Systems Biology 2012 6(Suppl 1):S5
  3. As protein domains are functional and structural units of proteins, a large proportion of protein-protein interactions (PPIs) are achieved by domain-domain interactions (DDIs), many computational efforts have ...

    Authors: Chen Chen, Jun-Fei Zhao, Qiang Huang, Rui-Sheng Wang and Xiang-Sun Zhang
    Citation: BMC Systems Biology 2012 6(Suppl 1):S7
  4. Noise, nonlinear interactions, positive and negative feedbacks within signaling pathways, time delays, protein oligomerization, and crosstalk between different pathways are main characters in the regulatory of...

    Authors: Canjun Wang, Ming Yi, Keli Yang and Lijian Yang
    Citation: BMC Systems Biology 2012 6(Suppl 1):S9
  5. Phase transition widely exists in the biological world, such as transformation of cell cycle phases, cell differentiation stages, disease development, and so on. Such a nonlinear phenomenon is considered as th...

    Authors: Tao Zeng and Luonan Chen
    Citation: BMC Systems Biology 2012 6(Suppl 1):S12

    The Erratum to this article has been published in BMC Systems Biology 2012 6:S23

  6. Membranous nephropathy is an important glomerular disease characterized by podocyte injury and proteinuria, but no metabolomics research was reported as yet. Here, we performed a parallel metabolomics study, b...

    Authors: Xianfu Gao, Wanjia Chen, Rongxia Li, Minfeng Wang, Chunlei Chen, Rong Zeng and Yueyi Deng
    Citation: BMC Systems Biology 2012 6(Suppl 1):S14
  7. Acupuncture has been practiced in China for thousands of years as part of the Traditional Chinese Medicine (TCM) and has gradually accepted in western countries as an alternative or complementary treatment. Ho...

    Authors: Yong Wang, Qiao-Feng Wu, Chen Chen, Ling-Yun Wu, Xian-Zhong Yan, Shu-Guang Yu, Xiang-Sun Zhang and Fan-Rong Liang
    Citation: BMC Systems Biology 2012 6(Suppl 1):S15
  8. Large amounts of data are being generated by high-throughput genome sequencing methods. But the rate of the experimental functional characterization falls far behind. To fill the gap between the number of sequ...

    Authors: Hari Krishna Yalamanchili, Quan-Wu Xiao and Junwen Wang
    Citation: BMC Systems Biology 2012 6(Suppl 1):S19